PKM2 is really a key player and regulator during the apoptotic pathways of several different cancers. B-cell lymphoma 2 (BCL2), a member of the BCL-2 relatives that's renowned for its anti-apoptotic capabilities [ninety one], was shown for being equally a immediate and oblique focus on for PKM2. Studies in human glioblastoma multiforme (GBM) cells
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